Research Papers

 

11. Atomic Substitution Reveals the Structural Basis for Substrate Adenine Recognition and Removal  by Adenine DNA Glycosylase.  Lee, S.; Verdine, G. L. 2009, Proc. Natl. Acad. Sci. USA  106, 18497.

10. Synthesis of C14,15-Dihydro-25-epi North Unit of Cephalostatin 1 via Redox Modifications of  Hecogenin Acetate.  Lee, S.; Jamieson, D.; Fuchs, P. L. Org. Lett. 2009, 11, 5.

 

 

9.  Synthesis and Structure of Duplex DNA Containing the Genotoxic Nucleobase Lesion N7- Methylguanine. Lee, S.; Bowman, R. B.; Ueno, Y.; Verdine, G. L. J. Am. Chem. Soc. 2008, 130, 11570.

    

8. Trapping and Structural Elucidation of a Very Advanced Intermediate in the Lesion-extrusion Pathway of hOGG1. (highlighted in Nat. Chem. Biol. 2008, 4, 395)  Lee, S.; Radom, C. T. Verdine, G. L. J. Am. Chem. Soc. 2008, 130, 7784.

 

7.  Structure of the Escherichia coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A  System for the Facile Structure Determination of Lesion-Containing DNA (Featured Article)  Bowman, B. R*.; Lee, S.* (*equal contribution); Wang, S.; Verdine, G. L. Structure 2008, 16,  1166.

6. A Concise Synthesis of 4′-F Nucleic Acids.

Lee, S.; Utammapinat, C.; Verdine, G. L. Org. Lett. 2007, 9, 5007.

 

 

5. In Situ Nitrosonium Ion Generation. Oximinylation of Enol Ethers from Steroidal Spiroketals. Introduction of C23 (R)-OH in Cephalostatin Intermediates.  Lee, S.; Fuchs, P. L. Can. J. Chem. 2006, 84, 1442.

 

 

4. An Efficient C-H Oxidation Protocol for the alpha-Hydroxylation of Cyclic Steroidal Ethers.

 Highly Efficient, Regio- and Stereoselective Oxyfunctionalization of Steroids by Cr[VI].

Lee, S.; Fuchs, P. L. Org. Lett. 2004, 6, 1437.

3. Chemospecific Chromium[VI] Catalyzed Oxidation of C-H Bonds at -40 oC.

Lee, S.; Fuchs, P. L. J. Am. Chem. Soc. 2002, 124, 13978.

 

2. The First Total Synthesis of Ritterazine M.  Lee, S.; Fuchs, P. L. Org. Lett. 2002, 4, 317.

1. Redox Functionalization of Steroid Spiroketals. Structure Correction of Ritterazine M.

Lee, S.; LaCour, T. G.; Lantrip, D. A.; Fuchs, P. L. Org. Lett. 2002, 4, 313.

    Review Papers

 

     3.  Chemistry of Trisdecacyclic Pyrazine Antineoplastics: The Cephalostatins and Ritterazines.

     Lee, S.; LaCour, T. G.; Fuchs, P. L. Chem. Rev. 2009,  109, 2275.

 

2. Chromyl acetate. Lee, S. Electronic Encyclopedia of Reagents for Organic Synthesis 2007.

 

1. Handbook of Organic Reagents: Reagents for Direct Functionalization of C-H Bonds.

 Lee, S. (book chapter) 2006 John Wiley, New York, Great Britain

 

    Patents

 

3. Synthesis of Nucleosides. Verdine, G. L.; Lee, S. US Patent Application No. 60/983550 (2008)

 

2. Catalytic Oxidation of C-H Bonds.  Lee, S.; Fuchs, P. L. US Patent 7,196,192 (2007)

 

1. Co-author of 17 Korean (ROK) Patents: A full list available upon request

The Lee Research Group

 

 

College of Pharmacy

The University of Texas at Austin

                          Chemical & Structural Biology of Nucleic Acids